ARCIMBOLDO-BORGES: Library search with PHASER and density modification and map interpretation with SHELXE
#Cluster | #Rotations | #Distinct Pdb | Top LLG | LLG Mean | Top Zscore | Zscore Mean |
---|---|---|---|---|---|---|
0 | 231 | 231 | 18.50 | 11.24 | 5.66 | 3.80 |
1 | 114 | 114 | 14.90 | 10.32 | 5.14 | 3.59 |
2 | 173 | 173 | 15.30 | 10.58 | 5.00 | 3.60 |
3 | 193 | 193 | 16.10 | 10.56 | 5.24 | 3.64 |
4 | 159 | 159 | 14.40 | 10.16 | 4.66 | 3.61 |
5 | 148 | 148 | 15.10 | 10.54 | 5.10 | 3.62 |
6 | 102 | 102 | 14.10 | 10.20 | 4.62 | 3.63 |
7 | 197 | 197 | 19.30 | 11.30 | 6.06 | 3.82 |
8 | 119 | 119 | 16.70 | 11.04 | 5.08 | 3.69 |
10 | 155 | 155 | 15.80 | 10.68 | 5.36 | 3.56 |
13 | 117 | 117 | 12.70 | 10.06 | 4.50 | 3.43 |
#Cluster | Rotation and Model Refinement | Translation Function | Packing | Rigid Body Refinement | Initial CC | Best Trace CC/aa | ||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
#Rots. | Top LLG | Mean LLG | Top Zscore | Mean Zscore | #Trans. | Top LLG | Mean LLG | Top Zscore | Mean Zscore | #Sol. | Top LLG | Mean LLG | Top Zscore | Mean Zscore | #Sol. | Top LLG | Mean LLG | Top TFZ== | Mean TFZ== | Before Refinement CC | After Refinement CC | MODE | Cycle | CC | #Res. traced | |
9 | 152 | 19.20 | 11.46 | 5.05 | 1.83 | 152 | 44.54 | 27.65 | 5.60 | 4.51 | 109 | 42.53 | 27.54 | 5.42 | 4.46 | 109 | 59.70 | 34.91 | 9.10 | 6.16 | 5.79 | 6.51 | ||||
0 | 462 | 18.50 | 10.39 | 5.66 | 1.90 | 462 | 47.42 | 26.14 | 5.51 | 4.41 | 339 | 47.42 | 25.82 | 5.46 | 4.38 | 339 | 60.00 | 32.11 | 10.80 | 5.95 | 5.93 | 6.54 | ||||
7 | 394 | 19.30 | 10.34 | 6.06 | 1.91 | 394 | 64.18 | 28.56 | 11.46 | 4.83 | 278 | 64.18 | 28.96 | 11.46 | 4.93 | 278 | 118.00 | 38.41 | 17.10 | 6.97 | 7.05 | 9.72 | FAST | 3 | 36.76 | 475 |
8 | 238 | 16.70 | 10.16 | 5.08 | 1.85 | 238 | 43.57 | 25.84 | 5.86 | 4.45 | 176 | 43.57 | 25.56 | 5.86 | 4.42 | 176 | 57.30 | 32.17 | 9.90 | 6.05 | 5.68 | 6.55 |
The current best solution is: frag589_0_0.pdb with FINALCC: 36.76 and n. residues traced 475
file is: /localdata1/TEST_TERESA/TEST_PHASER29/./ARCIMBOLDO_BORGES/./11_EXP_alixe/7/3/0/frag589_0_0_rbr_7_ref.pdb
[ARCIMBOLDO-BORGES] formfactors = FORMFACTORS XRAY aniso = True clusters = all n_clusters = 4 prioritize_phasers = True f_p1_label = sigf_p1_label = number_of_component = 1 number_of_component_p1 = rmsd = 0.8 rotation_clustering_algorithm = rot_matrices threshold_algorithm = 15 resolution_rotation = 1.0 sampling_rotation = -1.0 resolution_translation = 1.0 sampling_translation = -1 resolution_refinement = 1.0 sampling_refinement = -1 resolution_gyre = 1.0 exclude_llg = 0 exclude_zscore = 0 spacegroup = use_packing = True number_cycles_model_refinement = 2 tncs = True pack_clashes = 10 nice = 0 randomize_trans_per_rot = 0 nma = False make_positive_llg = False rotation_model_refinement = BOTH step_rmsd_decrease_gyre = 0.2 sigr = 0.0 sigt = 0.0 pack_tra = False base_sum_from_wd = True gyre_preserve_chains = True nma_p1 = False occ = False vrms = True vrms_gyre = False bfac = False bulk_fsol = -1 bulk_bsol = -1 gimble = True alixe_mode = one_step prioritize_occ = True solution_sorting_scheme = LLG sampling_gyre = -1 applytopnamefilter = True nodminitcc = True phs_fom_statistics = False savephs = True archivingasbigfile = False alixe = True filter_clusters_after_rot = False extend_with_random_atoms = False extend_with_secondary_structure = False parameters_elongation = 4.8 60 150 topfrf = 200 topftf = 70 toppack = -1 toprnp = 200 topexp = 40 force_core = -1 force_nsol = -1 force_exp = False ellg_target = 30.0 fixed_model = coiled_coil = False stop_if_solved = True unitcellcontentanalysis = False solventcontent = 0 shelxe_line = -m10 -a8 -s0.6 -v0 -t10 -q -o -y2.10 shelxe_line_last = -m10 -a1 -s0.55 -v0 -t10 -q -o -y2.10 -e1.60 molecular_weight = 70153.0 library_path = /localdata1/TEST_TERESA/TEST_PHASER29/./models/ f_label = F sigf_label = SIGF name_job = tere_shredsphere_phaser28_BORGESARCI [CONNECTION] distribute_computing = local_grid remote_frontend_passkey = ~/.ssh/id_rsa setup_bor_path = /xtal/cri4-software/borges/PY/current_setup.bor [GENERAL] mtz_p1_path = ent_path = /localdata1/TEST_TERESA/data_teresa/partial.ent pdb_path = working_directory = /localdata1/TEST_TERESA/TEST_PHASER29/./ARCIMBOLDO_BORGES/ mtz_path = /localdata1/TEST_TERESA/data_teresa/tere2.mtz hkl_path = /localdata1/TEST_TERESA/data_teresa/tere2.hkl [LOCAL] path_local_phaser = phenix.phaser path_local_shelxe = shelxe path_local_arcimboldo = ARCIMBOLDO_BORGES [ANOMALOUS] hkl_fa_path = none ins_fa_path = none expphasing = none nsites_expected = 0 ha_present_in_native = False recycle_ha = False sfac = none dsul = 0 specialpos = False rootanom = none dano_label = none sigdano_label = none nat_path = none peak_path = none infl_path = none hrem_path = none lrem_path = none sir_path = none sira_path = none before_path = none after_path = none minusz = False
Log file has not been found.Timestamp information Time MODE: ARCIMBOLDO-BORGES STEP: FRF 2018-07-09 17:04 Time MODE: ARCIMBOLDO-BORGES STEP: FRF 2018-07-09 17:04 Time MODE: ARCIMBOLDO-BORGES STEP: TABLE 2018-07-09 17:18 Time MODE: ARCIMBOLDO-BORGES STEP: FTF 2018-07-09 17:21 Time MODE: ARCIMBOLDO-BORGES STEP: PACK 2018-07-09 17:22 Time MODE: ARCIMBOLDO-BORGES STEP: RNP 2018-07-09 18:15 Time MODE: ARCIMBOLDO-BORGES STEP: INITCC 2018-07-09 18:21 Time MODE: ARCIMBOLDO-BORGES STEP: TABLE 2018-07-09 18:41 Time MODE: ARCIMBOLDO-BORGES STEP: FTF 2018-07-09 18:44 Time MODE: ARCIMBOLDO-BORGES STEP: PACK 2018-07-09 18:45 Time MODE: ARCIMBOLDO-BORGES STEP: RNP 2018-07-09 19:48 Time MODE: ARCIMBOLDO-BORGES STEP: INITCC 2018-07-09 19:59 Time MODE: ARCIMBOLDO-BORGES STEP: TABLE 2018-07-09 20:16 Time MODE: ARCIMBOLDO-BORGES STEP: FTF 2018-07-09 20:18 Time MODE: ARCIMBOLDO-BORGES STEP: PACK 2018-07-09 20:18 Time MODE: ARCIMBOLDO-BORGES STEP: RNP 2018-07-09 20:46 Time MODE: ARCIMBOLDO-BORGES STEP: INITCC 2018-07-09 20:49 Time MODE: ARCIMBOLDO-BORGES STEP: TABLE 2018-07-09 21:06 Time MODE: ARCIMBOLDO-BORGES STEP: FTF 2018-07-09 21:08 Time MODE: ARCIMBOLDO-BORGES STEP: PACK 2018-07-09 21:08 Time MODE: ARCIMBOLDO-BORGES STEP: RNP 2018-07-09 21:47 Time MODE: ARCIMBOLDO-BORGES STEP: INITCC 2018-07-09 21:51 Time MODE: ARCIMBOLDO-BORGES STEP: TABLE 2018-07-09 21:51 Time MODE: ARCIMBOLDO-BORGES STEP: FTF 2018-07-09 21:51 Time MODE: ARCIMBOLDO-BORGES STEP: PACK 2018-07-09 21:51 Time MODE: ARCIMBOLDO-BORGES STEP: RNP 2018-07-09 21:51 Time MODE: ARCIMBOLDO-BORGES STEP: INITCC 2018-07-09 21:51 Time MODE: ARCIMBOLDO-BORGES STEP: FAST_1_7 2018-07-11 00:03 Time MODE: ARCIMBOLDO-BORGES STEP: FAST_2_7 2018-07-11 02:05 Time MODE: ARCIMBOLDO-BORGES STEP: FAST_3_7 2018-07-11 05:16
Phaser crystallographic software.
McCoy, A. J., Grosse-Kunstleve, R. W., Adams, P. D., Winn, M. D., Storoni, L. C. & Read, R. J.
(2007) J Appl Cryst. 40, 658-674.
An introduction to experimental phasing of macromolecules illustrated by SHELX; new autotracing features.
Uson, I. & Sheldrick, G. M.
(2018) Acta Cryst. D74, 106-116.
Exploiting tertiary structure through local folds for ab initio phasing.
Sammito, M., Millan, C., Rodriguez, D. D., M. de Ilarduya, I., Meindl, K., De Marino, I., Petrillo, G., Buey, R. M., de Pereda, J. M., Zeth, K., Sheldrick, G. M. & Uson, I.
(2013) Nat Methods. 10, 1099-1101.
For online documentation and tutorials visit www.chango.ibmb.csic.es
For developer support send an email to bugs-borges@ibmb.csic.es
Crystallographic Methods Group
Structural Biology Unit
Molecular Biology Institute of Barcelona